Pharmaceutical inorganic chemistry 3 Semester 4 Notes | Download Free B Pharmacy Pdf Notes Semester Wise
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UNIT-I
Stereo isomerism
Optical isomerism –
Optical activity, enantiomerism, diastereoisomerism, meso compounds
Elements of symmetry, chiral and achiral molecules
DL system of nomenclature of optical isomers, sequence rules, RS system of nomenclature of optical isomers
Reactions of chiral molecules Racemic modification and resolution of racemic mixture.
Asymmetric
synthesis: partial and absolute
UNIT-II
Geometrical isomerism
Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)
Methods of determination of configuration of geometrical isomers.
Conformational isomerism in Ethane, n-Butane and Cyclohexane.
Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical activity.
Stereospecific and stereoselective
reactions
UNIT-III
Heterocyclic compounds:
Nomenclature and classification
Synthesis, reactions and medicinal uses of following compounds/derivatives
Pyrrole, Furan, and Thiophene
Relative aromaticity and
reactivity of Pyrrole, Furan and Thiophene
UNIT-IV
Synthesis, reactions and medicinal uses of following compounds/derivatives
Pyrazole, Imidazole, Oxazole and Thiazole.
Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine
Synthesis
and medicinal uses of Pyrimidine, Purine, azepines and their derivatives
UNIT-V
Reactions of synthetic importance
Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch reduction, Wolff Kishner reduction.
Oppenauer-oxidation and Dakin reaction.
Beckmanns rearrangement and Schmidt rearrangement.
Claisen-Schmidt condensation
UNIT-I
Stereo-isomerism
UNIT-II
Geometrical isomerism
UNIT-III
Heterocyclic compounds:
UNIT-IV
Synthesis, reactions and medicinal uses
UNIT-V
Reactions of synthetic importance
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