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1. Most potent narcotic antagonist is
a) Nalorphine
b) Naltrexone
c) Naloxone
d) Levorphanol
2. Which of the followings is a phenathrene derivative?
a) Fentanyl
b) Morhine
c) Methadone
d) Pentazocine
3. Which of the followings opioid analgesics is a strong mu recepator agonist ?
a) Pentazocine
b) Naloxone
c) Buprenorphine
d) Morphine
4. Which one Is the pure opioid antagonist among the followings ?
a) Nalorphine
b) Nalbuphine
c) Naloxone
d) Levallorphan
5. The drug naloxone
a) Produces morphine like activity
b) Produces respiratory depression
c) Induces constipation
d) Precipitates withdrawal systoms in morphine addicts
6. Which of the followings opioids analgesics is used in obstetric labor?
a) Fentanyl
b) Pentazocine
c) Meperidine
d) Buprenorphine
7. Which of the followings NSAIDs is a selective COX-2 inhibator ?
a) Diclofenac
b) Celecoxib
c) Indomethacin
d) Piroxicam
9. NSAID primarily promotes as an analgesic, not as an anti-inflammatory agent
a) Naproxen
b) Ibuprofen
c) Ketorolac
d) Piroxicam
10. Most of non-narcotic analgesic have
a) Anti-inflammatory effect
b) Analgesiceffect
c) Antipyretic effect
d) All of the above
11. ) Which of the followings ring is presenrt is sulindac ?
a) Indol
b) Indene
c) Isoxazole
d) Furan
12. Non-narcotic analgesic are all of the followings drugs EXPECT
a) Parecetamol
b) Acetylsalicylic acid
c) Butorphanol
d) Ketorolac
13. Non-narcotic analgesic are maninaly effective against pain associated with
a) Inflammation or tissue damage
b) Trauma
c) Myocardial infarction
d) Surgery
15. Ibuprofen is a
a) 2-(4-propylphenyl)propionic acid
b) 2-(4-isobytylphenyl)propionic acid
c) 2-(4-ethylphenyl)propionic acid
d) 2-(4-hexylphenyl)propionic acid
16. Which of the followings Sympathomimetics acts indirectly
a) Epinephrine
b) NE
c) Ephedrine
d) Methoxamine
17. Chemically alpha methyldopa is
a) 2-methyl-3 hydroxy-2-tyrosine
b) 6-methyl-4 hydroxy-2-tyrosine
c) 3-methyl-2 hydroxy-2-tyrosine
d) 3-hydroxy-α-methyl-2-tyrosine
18. DOPA is an important natural amino acid and precursor in the biosynthesis of
a) Nor-adrenaline
b) Adrenaline
c) Methyldopa
d) Dopamine
19. Catecholamine includes ther followings EXPECT
a) Norepinephrine
b) Ephedrine
c) Isoproternol
d) Epinephrine
20. Aromatic nucleus present in Propranolol
a) Naphthalene
b) Benzene
c) Anthracene
d) Pyridine
22. Propranolol is uded In the tretement all of the followings disease EXPECT
a) CVS disease
b) Hyperthyroidism
c) Migraine
d) Broncial asthma
23. β1 receptor stimulationm includes all of the followings effect EXPECT
a) Increase in heart ncontractility
b) Bronchodilation
c) Tachycardia
d) Increase in conduction velocity in the atrioventricular node
24. Salbutamol is synthesized from
a) Phenyl acetontrile
b) 4-Hydroxy propiophenone
c) Methyl salicylate
d) Mesitylene derivative
26. Indicate the location of M2 cholinorecepator type
a) Heart
b) Gland
c) Smooth muscle
d) Endothelium
27. Atropine contains
a) One asymmetric carbon
b) Three asymmetric carbon
c) Two asymmetric carbon
d) Four asymmetric carbon
28. Acetylcholine is not used in clinical practice beacause
a) It is very toxic
b) The doses require are very high
c) it is very rapidly hydrolyzed
d) it is very costly
29. Muscarine recepoator are located as
a) Autonomic ganglia
b) Skeletal muscle neuromuscular junction
c) Autonomic effector cells
d) Sensory carotid sinus baroreceptor zone
30. Indicate a reversible cholinsterase inhibator
a) Isoflurophate
b) Carbacol
c) Physostigamine
d) Parathion
31. What is often the first symptom of Parkinson disease
a) Headache
b) Nausea
c) Shaking of a hand or foot
d) Turning of the head
32. How is Parkinson disease treated?
a) Medicine
b) Surgery
c) Radiation
d) a and b
33. Which of the following beta-blockers is beta-1 selective with vasodilatation?
a) Propanolol
b) Carvedilol
c) Nebivolol
d) Atenolol
34. Which medication should be prescribe to all anginal patient to treat a acute attack ?
a) Isosorbide dinitrile
b) Nitroglycerin
c) Nifidepine
d) Parecetamol
35. Which of the followings precessor of nitroglycrine synthesis ?
a) Glycerol
b) Glycol
c) Glucose
d) Gluctiol
36. The calcium channel blocker belongs to diphenyl alkylamine category is
a) Diltizepam
b) Verapamil
c) Bepridil
d) Nitrendipine
37. The calcium channel blocker nifedipine is derivative of
a) Diaminopropranol ether
b) Diphenyl alkylamine
c) Benzothiazepine
d) Dihydropyridine
38. Which of the followings drugs is used in the tretement for the treatement of Glaucoma
a) Timolol
b) Atenolol
c) Propranolol
d) None of theses
39. Which of the followings drugs is ACE inhibitor
a) Timolol
b) Losartan
c) Gaunabenz
d) Lisinorpril
40. Heterocycles present in strcture of timolol is ?
a) Morpholin and thiadiazole
b) Thiadiazole and pyrrazole
c) Morpholin and oxadiazole
d) Oxadiazole and piperdine
41. Ther followings substance are considered to be a related to as an Eicosanoids
a) Prostaglandins
b) Leukotrienes
c) Thromboxanes
d) All of above
42. True about prostacycline
a) Vasoconstriction
b) Aggregation of Platelets
c) Decrease BP
d) Synthesis from vascular endothelium
43. QSAR study of Medicinal chemisrty Q stand for
a) Qualitative
b) Quantitative
c) Both
d) Quantum
44. Which of the following statements best describes a lead compound?
a) A compound that contains the element lead.
b) A compound from the research laboratory that is chosen to go forward for preclinical
and clinical trials
c) A molecule that shows some activity or property of interest and serves as the
starting point for the development of a drug
d) The first compound of a structural class of compounds to reach the marke
45. ) How many people will be selected for phase I trial?
a) The whole market will be under surveillance
b) 300-3000 people
c) 20-300 people
d) 20-50 people
46. In which of the followings phase of clinical trials healthy normal human volunteers
participate
a) Phase I
b) Phase II
c) Phase III
d) Phase IV
47. Meaning of P in QSAR equation stands for ____.
a) Permeability (b)
b) Partition coefficient
c) Porosity
d) Purity
48. QSAR stands for
a) Qualitative structure activity relationship
b) Quantitative structure action relationship
c) Quantitative structure activity relationship
d) Qualitative structure activity relativity
49. Clinical trials are performed on
a) Animals
b) Humans
c) Both
d) None of the above
50. Combinatorial chemistry or parallel synthesis can be useful at various stages of the drug
design / development process. Which of the following is NOT such a stage?
a) Finding a lead compound
b) Optimising a lead compound
c) structure determination of the lead compound
d) structure-activity relationships of the lead compoun
51. What is the name of the process by which compounds related to a promising compound
are made
on a larger scale?
a) Computational chemistry
b) Combinational chemistry
c) Lead optimisation
d) Improvement
52. Which of the following statements is true?
a) Parallel synthesis involves the synthesis of a large number of compounds using the same
reaction sequence, where there is a mixture of compounds in each reaction vessel.
b) Parallel synthesis involves the synthesis of a large number of compounds using the
same reaction sequence, where there is a different, single compound formed in each
reaction vessel.
c) Combinatorial synthesis involves the synthesis of a large number of compounds using a
variety of different synthetic routes to produce a mixture of compounds in each reaction
vessel.
d) A parallel synthesis carried out in a specified number of vessels will produce more
compounds than a combinatorial synthesis.
53. Structure which is used as the starting point for drugs design and development
a) Active Compunds
b) Pharmacophore
c) Lead compound
d) Orphagn drug
54. Indicate cholinestrease activator.
a) Pralidoxime
b) Edrophonium
c) Pilocrapine
d) Isofluorophate
55. The meachinsm of atropine action is
a) Competitive ganglion blockade
b) Competitive muscarinic blockade
c) Competitive Neuromuscular blockade
d) Non- Competitive Neuromuscular blockade
56. Parasympathomimetic drugs causes
a) Bronchodilation
b) Mydriasis
c) Bradycardia
d) Constipation
57. Most widely drug used for motion sickness is
a) Atropine
b) Hyoscyamine
c) Hyoscine
d) None of these
59. Which of the followings alpha -2- adrenorecetor agonist used in treatement of
Hypertension
a) Clonidine
b) Methyldopa
c) Both a & b
d) None of above
60. ) Which of the followings is also used in the management of cyanide poisoning ?
a) isosorbide dinitrate
b) Amyl nitrate
c) Nitroglycerin
d) isosorbide mononitrate
Check other important MCQs :-
MCQs From Pharmaceutical Engineering (include all chapters):- Click here
MCQs From Biopharmaceutics and Pharmacokinetics (include all chapters) :- Click here
MCQs From Tablet chapter :- Click here
MCQs From Pharmaceutical Jurisprudence (include all chapters):-Click here
MCQs on Introduction of Alkaloids:- Click here
Human Anatomy and Physiology-I :- Click here
MCQs on Introduction of Lipids and Resins:Click here
MCQs on Introduction of Volatile Oils:-Click Here
MCQs From Hospital and Clinical Pharmacy(include all chapters): Click here
MCQs on Introduction of Glycosides:-Click here
MCQs on Introduction of pharmacognosy :- Click here
Download and Read B pharmacy MCQs :- Click here
Check other important B Pharm Notes
Pharmaceutical Organic Chemistry :- Click here
Medicinal Chemistry :-Click here
Organic chemistry:- Click here
Pharmaceutical Analysis:- Click here
Cosmetic Notes:- Click here
Pharmacology:- Click here
Pharmaceutics :- Click here
Pharmacognosy:- Click here
Microbiology :-Downlaod
Pathophysiology :-Download
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